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GENERAL
TITLE
CRYSTAL STRUCTURE OF AKT1 IN COMPLEX WITH COVALENT-ALLOSTERIC AKT INHIBITOR BORUSSERTIB
DATE LAST MODIFIED
15 May 2019
RELEASE
20 Mar 2019
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.9
RESOLUTION RANGE LOW
46.89
PUBMED ID
DOI
10.1158/0008-5472.CAN-18-2861
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P31749 AKT1, PKB, RAC SPODOPTERA FRUGIPERDA HUMAN PROTEIN KINASE B,PKB,PROTEIN KINASE B ALPHA,PKB ALPHA,PROTO-ONCOGENE C-AKT,RAC-PK-ALPHA HUMAN
PROTEIN KINASE B,PKB,PROTEIN KINASE B ALPHA,PKB AL ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402