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GENERAL
TITLE
CRYSTAL STRUCTURE OF A HUMAN HDAC8 L6 LOOP MUTANT COMPLEXED WITH QUISINOSTAT
DATE LAST MODIFIED
28 Nov 2018
RELEASE
31 Oct 2018
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32
RESOLUTION RANGE HIGH
2.096
RESOLUTION RANGE LOW
46.08
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.8B01087
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q9BY41 HDAC8, HDACL1, CDA07 ESCHERICHIA COLI HUMAN HD8HDAC1 LOOP L6 (SGDRLGC) HUMAN
HD8HDAC1 LOOP L6 (SGDRLGC)
Mutations
Q9BY41 HDAC8, HDACL1, CDA07 ESCHERICHIA COLI HUMAN HD8HDAC1 LOOP L6 (SGDRLGC) HUMAN
HD8HDAC1 LOOP L6 (SGDRLGC)
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402