6I4Z

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 6I4Z_A

Chain 6I4Z_B

Chain 6I4Z_C

Chain 6I4Z_D

Chain 6I4Z_E

Chain 6I4Z_F

Chain 6I4Z_G

Chain 6I4Z_H

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GENERAL

TITLE

CRYSTAL STRUCTURE OF THE DISEASE-CAUSING P453L MUTANT OF THE HUMAN DIHYDROLIPOAMIDE DEHYDROGENASE

DATE LAST MODIFIED

11 Dec 2019

RELEASE

20 Nov 2019

OBSOLETE

CLASSIFICATION

OXIDOREDUCTASE

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1

RESOLUTION RANGE HIGH

2.34

RESOLUTION RANGE LOW

46.57

PUBMED ID

31334547

DOI

10.1093/HMG/DDZ177

PDBe

6I4Z

LIGANDS

963386

Chains

Target Protein	Gene	Expression System	Organism	Synonyms	Actions
P09622	DLD, GCSL, LAD, PHE3	ESCHERICHIA COLI BL21(DE3)	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SYSTEM LPROTEINMASWSHPQFEKGALEVLFQGPG	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SY ...	Mutations
P09622	DLD, GCSL, LAD, PHE3	ESCHERICHIA COLI BL21(DE3)	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SYSTEM LPROTEINMASWSHPQFEKGALEVLFQGPG	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SY ...	Mutations
P09622	DLD, GCSL, LAD, PHE3	ESCHERICHIA COLI BL21(DE3)	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SYSTEM LPROTEINMASWSHPQFEKGALEVLFQGPG	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SY ...	Mutations
P09622	DLD, GCSL, LAD, PHE3	ESCHERICHIA COLI BL21(DE3)	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SYSTEM LPROTEINMASWSHPQFEKGALEVLFQGPG	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SY ...	Mutations
P09622	DLD, GCSL, LAD, PHE3	ESCHERICHIA COLI BL21(DE3)	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SYSTEM LPROTEINMASWSHPQFEKGALEVLFQGPG	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SY ...	Mutations
P09622	DLD, GCSL, LAD, PHE3	ESCHERICHIA COLI BL21(DE3)	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SYSTEM LPROTEINMASWSHPQFEKGALEVLFQGPG	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SY ...	Mutations
P09622	DLD, GCSL, LAD, PHE3	ESCHERICHIA COLI BL21(DE3)	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SYSTEM LPROTEINMASWSHPQFEKGALEVLFQGPG	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SY ...	Mutations
P09622	DLD, GCSL, LAD, PHE3	ESCHERICHIA COLI BL21(DE3)	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SYSTEM LPROTEINMASWSHPQFEKGALEVLFQGPG	HUMAN	DIHYDROLIPOAMIDE DEHYDROGENASE,GLYCINE CLEAVAGE SY ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402