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GENERAL
TITLE
POLYPHARMACOLOGY OF EPACADOSTAT: A POTENT AND SELECTIVE INHIBITOR OF THE TUMOR ASSOCIATED CARBONIC ANHYDRASES IX AND XII
DATE LAST MODIFIED
22 May 2019
RELEASE
15 May 2019
OBSOLETE
CLASSIFICATION
LIGASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.15
RESOLUTION RANGE LOW
41.06
PUBMED ID
DOI
10.1039/C8CC09568J
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P00918 CA2 ESCHERICHIA COLI HUMAN CARBONATE DEHYDRATASE II,CARBONIC ANHYDRASE C,CAC,CARBONICANHYDRASE II,CA-II HUMAN
CARBONATE DEHYDRATASE II,CARBONIC ANHYDRASE C,CAC, ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402