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GENERAL
TITLE
COVALENT LABELING OF RVDR-LBD BY TURN-ON FLUORESCENT PROBE MEDIATED BY CONJUGATE ADDITION AND CYCLIZATION
DATE LAST MODIFIED
8 Apr 2020
RELEASE
12 Feb 2020
OBSOLETE
CLASSIFICATION
HORMONE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
41.75
PUBMED ID
DOI
10.1016/J.CHEMBIOL.2020.01.006
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P13053 VDR, NR1I1 ESCHERICHIA COLI RAT VDR,1,25-DIHYDROXYVITAMIN D3 RECEPTOR,NUCLEAR RECEPTORSUBFAMILY 1 GROUP I MEMBER 1,VDR,1,25-DIHYDROXYVITAMIN D3 RECEPTOR,NUCLEAR RECEPTOR SUBFAMILY 1 GROUP I MEMBER 1 RAT
VDR,1,25-DIHYDROXYVITAMIN D3 RECEPTOR,NUCLEAR RECE ...
Mutations
Q15648 -- -- HUMAN ACTIVATOR-RECRUITED COFACTOR 205 KDA COMPONENT,ARC205,MEDIATOR COMPLEX SUBUNIT 1,PEROXISOME PROLIFERATOR-ACTIVATEDRECEPTOR-BINDING PROTEIN,PPAR-BINDING PROTEIN,THYROID HORMONERECEPTOR-ASSOCIATED PROTEIN COMPLEX 220 KDA COMPONENT,TRAP220,THYROIDRECEPTOR-INTERACTING PROTEIN 2,TRIP-2,VITAMIN D RECEPTOR-INTERACTINGPROTEIN COMPLEX COMPONENT DRIP205,P53 REGULATORY PROTEIN RB18A HUMAN
ACTIVATOR-RECRUITED COFACTOR 205 KDA COMPONENT,ARC ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402