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GENERAL
TITLE
CRYSTAL STRUCTURE OF BACE1 IN COMPLEX WITH N-{3-[(4S)-2-AMINO-4- METHYL-5,6-DIHYDRO-4H-1,3-THIAZIN-4-YL]-4-FLUOROPHENYL}-5- CHLOROPYRIDINE-2-CARBOXAMIDE
DATE LAST MODIFIED
-
RELEASE
28 Aug 2019
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61 2 2
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.9B00309
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
P56817 BACE1, BACE, KIAA1149 ESCHERICHIA COLI HUMAN ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECURSORPROTEIN CLEAVING ENZYME 1,BETA-SITE APP CLEAVING ENZYME 1,MEMAPSIN-2,MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 2 HUMAN
ASPARTYL PROTEASE 2,ASP 2,BETA-SITE AMYLOID PRECUR ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402