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3D Structure View

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GENERAL
TITLE
BACE2 XAPERONE COMPLEX WITH N-{3-[(5R)-3-AMINO-5-METHYL-9,9-DIOXO-2, 9LAMBDA6-DITHIA-4-AZASPIRO[5.5]UNDEC-3-EN-5-YL]-4-FLUOROPHENYL}-5- (FLUOROMETHOXY)PYRAZINE-2-CARBOXAMIDE
DATE LAST MODIFIED
-
RELEASE
28 Aug 2019
OBSOLETE
CLASSIFICATION
HYDROLASE/IMMUNE SYSTEM
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.53
RESOLUTION RANGE LOW
61.51
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.9B00309

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonymsActions
Q9Y5Z0 BACE2, AEPLC, ALP56, ASP21, CDA13, UNQ418/PRO852 ESCHERICHIA COLI HUMAN ASPARTIC-LIKE PROTEASE 56 KDA,ASPARTYL PROTEASE 1,ASP 1,BETA-SITE AMYLOID PRECURSOR PROTEIN CLEAVING ENZYME 2,BETA-SITE APPCLEAVING ENZYME 2,DOWN REGION ASPARTIC PROTEASE,DRAP,MEMAPSIN-1,MEMBRANE-ASSOCIATED ASPARTIC PROTEASE 1,THETA-SECRETASE HUMAN
ASPARTIC-LIKE PROTEASE 56 KDA,ASPARTYL PROTEASE 1, ...
Mutations
-- -- HUMAN -- HUMAN --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402