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GENERAL
TITLE
CRYSTAL STRUCTURE OF DYRK1A WITH SMALL MOLECULE INHIBITOR
DATE LAST MODIFIED
11 Aug 2021
RELEASE
26 Jun 2019
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.38
RESOLUTION RANGE LOW
110.03
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.0C00279

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q13627 DYRK1A, DYRK, MNB, MNBH ESCHERICHIA COLI BL21(DE3) HUMAN
DUAL SPECIFICITY YAK1-RELATED KINASE,HP86,PROTEIN ...
Mutations
P9WPP7 DYRK1A, DYRK, MNB, MNBH ESCHERICHIA COLI BL21(DE3) HUMAN
DUAL SPECIFICITY YAK1-RELATED KINASE,HP86,PROTEIN ...
Q13627 DYRK1A, DYRK, MNB, MNBH ESCHERICHIA COLI BL21(DE3) HUMAN
DUAL SPECIFICITY YAK1-RELATED KINASE,HP86,PROTEIN ...
Mutations
P03366 DYRK1A, DYRK, MNB, MNBH ESCHERICHIA COLI BL21(DE3) HUMAN
DUAL SPECIFICITY YAK1-RELATED KINASE,HP86,PROTEIN ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402