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GENERAL
TITLE
A DUAL MECHANISM OF ACTION OF AT-527 AGAINST SARS-COV-2 POLYMERASE
DATE LAST MODIFIED
-
RELEASE
16 Feb 2022
OBSOLETE
CLASSIFICATION
VIRAL PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.98
RESOLUTION RANGE LOW
2.98
PUBMED ID
DOI
10.1038/S41467-022-28113-1
PDBe
--
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P0C6X7-Nsp12 REP, 1A-1B SPODOPTERA FRUGIPERDA SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS
POL,RDRP,NON-STRUCTURAL PROTEIN 12,NSP12
P0C6U8-Nsp8 REP, 1A-1B ESCHERICHIA COLI SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS
NSP8
P0C6X7-Nsp7 REP, 1A-1B ESCHERICHIA COLI SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS
NSP7
P0C6U8-Nsp8 REP, 1A-1B ESCHERICHIA COLI SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS
NSP8
-- -- SYNTHETIC CONSTRUCT --
-- -- SYNTHETIC CONSTRUCT --
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402