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GENERAL
TITLE
CRYOEM STRUCTURE OF PRMT5 BOUND TO COVALENT PBM-SITE INHIBITOR BRD- 6988
DATE LAST MODIFIED
25 Aug 2021
RELEASE
17 Mar 2021
OBSOLETE
CLASSIFICATION
TRANSFERASE/INHIBITOR
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.39
RESOLUTION RANGE LOW
2.39
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.1C00507
PDBe
--
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P53608 | PRMT5, HRMT1L5, IBP72, JBP1, SKB1 | SPODOPTERA FRUGIPERDA | HUMAN | 72 KDA ICLN-BINDING PROTEIN,HISTONE-ARGININE N-MET ... | ||
| Q9BQA1 | WDR77, MEP50, WD45, HKMT1069, NBLA10071 | SPODOPTERA FRUGIPERDA | HUMAN | MEP-50,ANDROGEN RECEPTOR COFACTOR P44,WD REPEAT-CO ... | Mutations | |
| P53608 | PRMT5, HRMT1L5, IBP72, JBP1, SKB1 | SPODOPTERA FRUGIPERDA | HUMAN | 72 KDA ICLN-BINDING PROTEIN,HISTONE-ARGININE N-MET ... | ||
| Q9BQA1 | WDR77, MEP50, WD45, HKMT1069, NBLA10071 | SPODOPTERA FRUGIPERDA | HUMAN | MEP-50,ANDROGEN RECEPTOR COFACTOR P44,WD REPEAT-CO ... | Mutations | |
| O14744 | PRMT5, HRMT1L5, IBP72, JBP1, SKB1 | SPODOPTERA FRUGIPERDA | HUMAN | 72 KDA ICLN-BINDING PROTEIN,HISTONE-ARGININE N-MET ... | Mutations | |
| Q9BQA1 | WDR77, MEP50, WD45, HKMT1069, NBLA10071 | SPODOPTERA FRUGIPERDA | HUMAN | MEP-50,ANDROGEN RECEPTOR COFACTOR P44,WD REPEAT-CO ... | Mutations | |
| O14744 | PRMT5, HRMT1L5, IBP72, JBP1, SKB1 | SPODOPTERA FRUGIPERDA | HUMAN | 72 KDA ICLN-BINDING PROTEIN,HISTONE-ARGININE N-MET ... | Mutations | |
| Q9BQA1 | WDR77, MEP50, WD45, HKMT1069, NBLA10071 | SPODOPTERA FRUGIPERDA | HUMAN | MEP-50,ANDROGEN RECEPTOR COFACTOR P44,WD REPEAT-CO ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402