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GENERAL
TITLE
FIRST-IN-CLASS SMALL MOLECULE INHIBITORS OF POLYCOMB REPRESSIVE COMPLEX 1 (PRC1) RING DOMAIN
DATE LAST MODIFIED
7 Jul 2021
RELEASE
16 Jun 2021
OBSOLETE
CLASSIFICATION
GENE REGULATION
EXPERIMENT TYPE
NMR
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
--
RESOLUTION RANGE LOW
--
PUBMED ID
DOI
10.1038/S41589-021-00815-5
PDBe
--
LIGANDS
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q99496 RNF2, BAP1, DING, HIPI3, RING1B ESCHERICHIA COLI HUMAN
HUNTINGTIN-INTERACTING PROTEIN 2-INTERACTING PROTE ...
Mutations
Q12415 BMI1, PCGF4, RNF51 ESCHERICHIA COLI HUMAN
POLYCOMB GROUP RING FINGER PROTEIN 4,RING FINGER P ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402