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GENERAL
TITLE
CRYSTAL STRUCTURE OF PI3KALPHA IN COMPLEX WITH THE INHIBITOR NVP- BYL719
DATE LAST MODIFIED
-
RELEASE
24 Aug 2022
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.499
RESOLUTION RANGE LOW
50
PUBMED ID
-
DOI
--
PDBe
--
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P42336 PIK3CA SPODOPTERA FRUGIPERDA HUMAN
PI3-KINASE SUBUNIT ALPHA,PI3K-ALPHA,PI3KALPHA,PTDI ...
Mutations
P27986 PIK3R1, GRB1 SPODOPTERA FRUGIPERDA HUMAN
PI3-KINASE REGULATORY SUBUNIT ALPHA,PI3K REGULATOR ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402