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GENERAL
TITLE
CRYSTAL STRUCTURE OF IVOSIDENIB-RESISTANT IDH1 VARIANT R132C S280F IN COMPLEX WITH NADPH AND CA2+/2-OXOGLUTARATE
DATE LAST MODIFIED
19 Oct 2022
RELEASE
13 Jul 2022
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
2.1
RESOLUTION RANGE LOW
71.95
PUBMED ID
DOI
10.1038/S41467-022-32436-4
LIGANDS
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O74036 IDH1, PICD ESCHERICHIA COLI BL21(DE3) HUMAN
IDH,CYTOSOLIC NADP-ISOCITRATE DEHYDROGENASE,IDP,NA ...
O74036 IDH1, PICD ESCHERICHIA COLI BL21(DE3) HUMAN
IDH,CYTOSOLIC NADP-ISOCITRATE DEHYDROGENASE,IDP,NA ...
O74036 IDH1, PICD ESCHERICHIA COLI BL21(DE3) HUMAN
IDH,CYTOSOLIC NADP-ISOCITRATE DEHYDROGENASE,IDP,NA ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402