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GENERAL
TITLE
CRYSTAL STRUCTURE OF ANGIOTENSIN-1 CONVERTING ENZYME N-DOMAIN IN COMPLEX WITH DUAL ACE/NEP INHIBITOR AD013
DATE LAST MODIFIED
9 Mar 2022
RELEASE
16 Feb 2022
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
1.7
RESOLUTION RANGE LOW
73.97
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.1C01924
LIGANDS
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P12821 ACE, DCP, DCP1 CRICETULUS GRISEUS HUMAN
ACE,DIPEPTIDYL CARBOXYPEPTIDASE I,KININASE II
Mutations
P02883 ACE, DCP, DCP1 CRICETULUS GRISEUS HUMAN
ACE,DIPEPTIDYL CARBOXYPEPTIDASE I,KININASE II
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402