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GENERAL
TITLE
CRYSTAL STRUCTURE OF HPK1 IN COMPLEX WITH GNE1858
DATE LAST MODIFIED
9 Feb 2022
RELEASE
5 Jan 2022
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
1.5
RESOLUTION RANGE LOW
42.47
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.1C00473
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q92918 MAP4K1, HPK1 SPODOPTERA FRUGIPERDA HUMAN
HKP1, HEMATOPOIETIC PROGENITOR KINASE, MAPK/ERK KI ...
Mutations
P21816 MAP4K1, HPK1 SPODOPTERA FRUGIPERDA HUMAN
HKP1, HEMATOPOIETIC PROGENITOR KINASE, MAPK/ERK KI ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402