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GENERAL
TITLE
DFRA1 COMPLEXED WITH NADPH AND 5-(3-(7-(4-(AMINOMETHYL)PHENYL) BENZO[D][1,3]DIOXOL-5-YL)BUT-1-YN-1-YL)-6-ETHYLPYRIMIDINE-2,4-DIAMINE (UCP1223)
DATE LAST MODIFIED
-
RELEASE
25 May 2022
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
1.44
RESOLUTION RANGE LOW
62.67
PUBMED ID
DOI
10.1038/S42003-022-03384-Y
LIGANDS
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P40969 DHFRI ESCHERICHIA COLI BL21(DE3) ESCHERICHIA COLI
DIHYDROFOLATE REDUCTASE TYPE I,TRIMETHOPRIM RESIST ...
P02309 DHFRI ESCHERICHIA COLI BL21(DE3) ESCHERICHIA COLI
DIHYDROFOLATE REDUCTASE TYPE I,TRIMETHOPRIM RESIST ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402