7RGO logo

7RGO

3D Structure View

Loading...

More Info

GENERAL
TITLE
DFRA5 COMPLEXED WITH NADPH AND 4'-CHLORO-3'-(4-(2,4-DIAMINO-6- ETHYLPYRIMIDIN-5-YL)BUT-3-YN-2-YL)-[1,1'-BIPHENYL]-4-CARBOXAMIDE (UCP1228)
DATE LAST MODIFIED
-
RELEASE
25 May 2022
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 43
RESOLUTION RANGE HIGH
1.92
RESOLUTION RANGE LOW
32.95
PUBMED ID
DOI
10.1038/S42003-022-03384-Y
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P11731 DHFRV ESCHERICHIA COLI ESCHERICHIA COLI
DIHYDROFOLATE REDUCTASE TYPE V
Mutations
P31783 DHFRV ESCHERICHIA COLI ESCHERICHIA COLI
DIHYDROFOLATE REDUCTASE TYPE V
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402