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GENERAL
TITLE
STRUCTURE OF THE OREXIN-2 RECEPTOR(OX2R) BOUND TO TAK-925, GI AND SCFV16
DATE LAST MODIFIED
6 Jul 2022
RELEASE
25 May 2022
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
3.17
RESOLUTION RANGE LOW
3.17
PUBMED ID
DOI
10.1038/S41467-022-30601-3
PDBe
--
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P00698 GNAI1 TRICHOPLUSIA NI HUMAN
ADENYLATE CYCLASE-INHIBITING G ALPHA PROTEIN
P00388 GNB1 TRICHOPLUSIA NI CATTLE
TRANSDUCIN BETA CHAIN 1
O60674 -- TRICHOPLUSIA NI SYNTHETIC CONSTRUCT --
Q8NHS0 GNG2 TRICHOPLUSIA NI CATTLE
G GAMMA-I
O43614 HCRTR2 SPODOPTERA HUMAN
OX-2-R,OX2-R,OX2R,HYPOCRETIN RECEPTOR TYPE 2
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402