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GENERAL
TITLE
NATIVE HUMAN TSH BOUND TO HUMAN THYROTROPIN RECEPTOR IN COMPLEX WITH MINIGS399 (COMPOSITE STRUCTURE)
DATE LAST MODIFIED
5 Oct 2022
RELEASE
3 Aug 2022
OBSOLETE
CLASSIFICATION
MEMBRANE PROTEIN
EXPERIMENT TYPE
ELECTRON MICROSCOPY
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
2.9
RESOLUTION RANGE LOW
2.9
PUBMED ID
DOI
10.1038/S41586-022-05159-1
PDBe
--
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P01215 -- -- HUMAN
ANTERIOR PITUITARY GLYCOPROTEIN HORMONES COMMON SU ...
Mutations
P01222 -- -- HUMAN
THYROID-STIMULATING HORMONE SUBUNIT BETA,TSH-B,TSH ...
Mutations
-- ESCHERICHIA COLI LAMA GLAMA --
P0DOY3 TSHR HOMO SAPIENS HUMAN --
P63092 GNAS, GNAS1, GSP HOMO SAPIENS HUMAN
ADENYLATE CYCLASE-STIMULATING G ALPHA PROTEIN
Mutations
P62873 GNB1 TRICHOPLUSIA NI HUMAN
TRANSDUCIN BETA CHAIN 1
Mutations
P59768 GNG2 TRICHOPLUSIA NI HUMAN
G GAMMA-I
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402