7VSI

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Bioassembly 7VSI_1

Chain 7VSI_A

Chain 7VSI_B

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GENERAL

TITLE

STRUCTURE OF HUMAN SGLT2-MAP17 COMPLEX BOUND WITH EMPAGLIFLOZIN

DATE LAST MODIFIED

16 Feb 2022

RELEASE

15 Dec 2021

OBSOLETE

CLASSIFICATION

TRANSPORT PROTEIN

EXPERIMENT TYPE

ELECTRON MICROSCOPY

SPACE GROUP

P 1

RESOLUTION RANGE HIGH

2.95

RESOLUTION RANGE LOW

2.95

PUBMED ID

DOI

10.1038/S41586-021-04212-9

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	Q9NRG4	SLC5A2, SGLT2	HOMO SAPIENS	HUMAN	NA(+)/GLUCOSE COTRANSPORTER 2,LOW AFFINITY SODIUM- ...
	Q13113	PDZK1IP1, MAP17	HOMO SAPIENS	HUMAN	17 KDA MEMBRANE-ASSOCIATED PROTEIN,PROTEIN DD96	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402