FEATURES

FAMILY

DESCRIPTION

Also known as TRPDC_RUMGV, RUMGNA_01526. Catalyzes the decarboxylation of tryptophan to tryptamine. Tryptamine is a neurotransmitter that induces the release of serotonin, which is suggested to modulate gastrointestinal motility. Therefore, the tryptophan decarboxylase from the gut bacteria Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) may influence host brain and behavior. Has weak activity with tyrosine and phenylalanine. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

RUMGNA_01526

Tryptophan decarboxylase

Mutations

Mutation(s) distribution

Mutations table

Search Mutation