FEATURES

FAMILY

DESCRIPTION

Also known as CACB4_HUMAN, CACNB4, CACNLB4. The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma (PubMed:11880487). Interacts with FASLG (PubMed:19807924). Interacts with CBARP (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CACNB4

Voltage-dependent L-type calcium channel subunit beta-4

CACNB4

Molecular Synopsis