FEATURES

FAMILY

Monocarboxylate porter (TC 2.A.1.13) family

DESCRIPTION

Also known as MOT2_HUMAN, SLC16A7, MCT2. Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Functions as high-affinity pyruvate transporter. Interacts with GRID2IP (By similarity). Interacts with EMB (By similarity). Interacts with isoform 2 of BSG (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SLC16A7

Monocarboxylate transporter 2

SLC16A7

Molecular Synopsis