FEATURES

FAMILY

DESCRIPTION

Also known as RAMP3_HUMAN, RAMP3. Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) and GPER1 to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL. Heterodimer of CALCRL and RAMP3 (By similarity). Interacts with GPER1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RAMP3

Receptor activity-modifying protein 3

RAMP3

Molecular Synopsis