FEATURES

DESCRIPTION

Also known as S14L2_HUMAN, SEC14L2, C22orf6, KIAA1186, KIAA1658. Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell. Monomer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SEC14L2

SEC14-like protein 2

SEC14L2

Molecular Synopsis