FEATURES

FAMILY

DESCRIPTION

Also known as AL1A2_HUMAN, ALDH1A2, RALDH2. Converts retinaldehyde to retinoic acid (PubMed:29240402). Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Can metabolize octanal and decanal, but has only very low activity with benzaldehyde, acetaldehyde and propanal. Displays complete lack of activity with citral (By similarity). Homotetramer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ALDH1A2

Retinal dehydrogenase 2

ALDH1A2

Molecular Synopsis