FEATURES

FAMILY

DESCRIPTION

Also known as S1PR2_HUMAN, S1PR2, EDG5. Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P) (PubMed:10617617). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues (PubMed:10617617). When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis (PubMed:10617617). Receptor for the chemokine-like protein FAM19A5 (PubMed:29453251). Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

S1PR2

Sphingosine 1-phosphate receptor 2

S1PR2

Molecular Synopsis