FEATURES

FAMILY

DESCRIPTION

Also known as OTC_HUMAN, OTC. Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline (PubMed:6372096, PubMed:8112735, PubMed:2556444). The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion (PubMed:2556444). Homotrimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

OTC

Ornithine transcarbamylase, mitochondrial

OTC

Molecular Synopsis