FEATURES

FAMILY

DESCRIPTION

Also known as EPO_HUMAN, EPO. Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

EPO

Erythropoietin

EPO

Molecular Synopsis