FEATURES

FAMILY

DESCRIPTION

Also known as YAJC_ECOLI, yajC. The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes (PubMed:27435098). The SecYEG complex is essential for assembly of a number of proteins and complexes, assembly is facilitated in the presence of the SecDF-YajC-YidC subcomplex (PubMed:27435098). Part of the SecDF-YidC-YajC translocase complex; YajC is also present in a homooligomeric complex in excess of the other components (PubMed:16079137). The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL) (PubMed:27435098). The stoichiometry of the super complex may be SecYEG:YidC:SecDF 4:3:1, YajC is in the reconstituted complex (with SecDF) but as no antibody is available it could not be quantified (PubMed:27435098).

EXTERNAL LINKS

yajC

Sec translocon accessory complex subunit YajC

yajC

Molecular Synopsis