FEATURES

FAMILY

DESCRIPTION

Also known as RNAS2_HUMAN, RNASE2, EDN, RNS2. This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities. Interacts with and forms a tight 1:1 complex with RNH1. Dimerization of two such complexes may occur.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RNASE2

Non-secretory ribonuclease

RNASE2

Molecular Synopsis