FEATURES

FAMILY

DESCRIPTION

Also known as ACTN1_HUMAN, ACTN1. F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Homodimer; antiparallel. Interacts with MYOZ2, TTID and LPP (PubMed:10369880, PubMed:11114196, PubMed:12615977). Interacts with DDN (PubMed:16464232). Interacts with PSD. Interacts with MICALL2 (By similarity). Interacts with DNM2 and CTTN. Interacts with PDLIM1. Interacts with PDLIM2. Interacts with PDLIM4 (via PDZ domain) (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ACTN1

Alpha-actinin-1

ACTN1

Molecular Synopsis