FEATURES

FAMILY

adenylyl cyclase class-4/guanylyl cyclase family

DESCRIPTION

Also known as ANPRA_HUMAN, NPR1, ANPRA. Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

NPR1

Atrial natriuretic peptide receptor 1

NPR1

Molecular Synopsis