FEATURES

DESCRIPTION

Also known as VCAM1_HUMAN, VCAM1. Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

VCAM1

Vascular cell adhesion protein 1

VCAM1

Molecular Synopsis