FEATURES

FAMILY

flavoprotein pyridine nucleotide cytochrome reductase family

DESCRIPTION

Also known as NB5R3_RAT, Cyb5r3, Dia1. Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. Component of a complex composed of cytochrome b5, NADH-cytochrome b5 reductase (CYB5R3) and MTARC2 (By similarity). Interacts with MTLN; the interaction is required to maintain cellular lipid composition and leads to stimulation of mitochondrial respiratory complex I activity (By similarity).

Also known as NB5R3_RAT, Cyb5r3, Dia1. Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. Component of a comple ...

EXTERNAL LINKS

uniprot
enzyme classification

Cyb5r3

Mutations

Mutation(s) distribution

Mutations table