FEATURES

FAMILY

DESCRIPTION

Also known as MAK_HUMAN, MAK. Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells. Interacts with RP1 (By similarity). Interacts with AR and CDK20. Found in a complex containing MAK, AR and NCOA3. Interacts with FZR1 (via WD repeats).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MAK

Serine/threonine-protein kinase MAK

MAK

Molecular Synopsis