FEATURES

FAMILY

DESCRIPTION

Also known as NK2R_HUMAN, TACR2, NK2R, NKNAR, TAC2R. This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

TACR2

Substance-K receptor

TACR2

Molecular Synopsis