FEATURES

FAMILY

DESCRIPTION

Also known as KAPCG_HUMAN, PRKACG. Phosphorylates a large number of substrates in the cytoplasm and the nucleus. A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PRKACG

cAMP-dependent protein kinase catalytic subunit gamma

PRKACG

Molecular Synopsis