FEATURES

FAMILY

DESCRIPTION

Also known as PTAFR_HUMAN, PTAFR, PAFR. Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. Interacts with ARRB1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PTAFR

Platelet-activating factor receptor

PTAFR

Molecular Synopsis