FEATURES

FAMILY

DESCRIPTION

Also known as 3BHS2_HUMAN, HSD3B2, HSDB3B. 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

HSD3B2

3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2

HSD3B2

Molecular Synopsis