FEATURES

FAMILY

DESCRIPTION

Also known as SSR1_HUMAN, SSTR1. Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins. Interacts with SKB1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SSTR1

Somatostatin receptor type 1

SSTR1

Molecular Synopsis