FEATURES

FAMILY

DESCRIPTION

Also known as SSR4_HUMAN, SSTR4. Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SSTR4

Somatostatin receptor type 4

SSTR4

Molecular Synopsis