FEATURES

FAMILY

DESCRIPTION

Also known as PEDF_HUMAN, SERPINF1, PEDF. Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SERPINF1

Pigment epithelium-derived factor

SERPINF1

Molecular Synopsis