FEATURES

FAMILY

DESCRIPTION

Also known as MDHC_HUMAN, MDH1, MDHA. Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH (PubMed:3052244). Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation (PubMed:31538237). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MDH1

Malate dehydrogenase, cytoplasmic

MDH1

Molecular Synopsis