FEATURES

FAMILY

DESCRIPTION

Also known as PACR_HUMAN, ADCYAP1R1. This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. Interacts (via N-terminal extracellular domain) with ADCYAP1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ADCYAP1R1

Pituitary adenylate cyclase-activating polypeptide type I receptor

ADCYAP1R1

Molecular Synopsis