FEATURES

FAMILY

DESCRIPTION

Also known as IF1AX_HUMAN, EIF1AX, EIF1A, EIF4C. Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (Microbial infection) Interacts with human respiratory syncytial virus (HRSV) nucleoprotein; this interaction recruits EIF1AX to the viral replication complex to facilitate viral genomic RNA synthesis and virus production.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

EIF1AX

Eukaryotic translation initiation factor 1A, X-chromosomal

EIF1AX

Molecular Synopsis