FEATURES

FAMILY

DESCRIPTION

Also known as P2RY1_HUMAN, P2RY1. Receptor for extracellular adenine nucleotides such as ADP (PubMed:9442040, PubMed:9038354, PubMed:25822790). In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation (PubMed:9442040).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

P2RY1

P2Y purinoceptor 1

P2RY1

Molecular Synopsis