FEATURES

FAMILY

DESCRIPTION

Also known as COATR_MYCTU, Rv3272. Probably involved in fatty acid metabolism. Binds to fatty acyl-CoAs of varying carbon chain lengths, with the highest binding affinity for palmitoyl-CoA (C16:0). In vitro, alters the cell wall lipid profile and protects mycobacteria from acidic, oxidative and antibiotic stress. May play a significant role in host-pathogen interaction. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

Rv3272

Probable fatty acyl-CoA transferase Rv3272

Mutations

Mutation(s) distribution

Mutations table

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