FEATURES

FAMILY

adenylyl cyclase class-4/guanylyl cyclase family

DESCRIPTION

Also known as ADCY2_HUMAN, ADCY2, KIAA1060. Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642). Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors (By similarity). Interacts with RAF1 (PubMed:15385642). Interacts with GNAS. Interacts with the G protein beta and gamma subunit complex (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ADCY2

Adenylate cyclase type 2

ADCY2

Molecular Synopsis