FEATURES

FAMILY

DESCRIPTION

Also known as PTK7_HUMAN, PTK7, CCK4. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. Interacts with CTNNB1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

PTK7

Inactive tyrosine-protein kinase 7

PTK7

Molecular Synopsis